- The early Mercury flights developed the idea of putting a human in a capsule on top of an ICBM to see what happens at altitude and during re-entry.
- Later Mercury flights experimented with de-orbiting techniques. (The early flights didn't need that because the ICBMs that launched the first people into space did so on a ballistic trajectory – they never achieved orbit.)
- With Gemini we figured out things like endurance (what is it like to have humans in space for weeks), rendezvous and docking (incredibly difficult), and extravehicular activities (preparation for walking on another astronomical body.)
- Early Apollo was focused entirely on solving multi-stage flights without humans on board.
- With Apollo 7 we verified the command module was good enough to attempt to send a few laps around the moon, which happened with Apollo 8, while we were still waiting for a fully functioning lander.
- Apollo 9 was a dry run of the entire moon landing sequence – except in low Earth orbit.
- Apollo 10 repeated the same exercise from Apollo 9 except in Lunar orbit.
- Apollo 11 is often considered the first moon landing, but from the perspective of the program, it was really just another experiment: can we repeat Apollo 10 except also make a brief touch-and-go anywhere on the lunar surface?
- Even Apollo 12 isn't really a moon landing proper, but another experiment: can we repeat Apollo 11 but now also make a precision touchdown?
It wasn't until somewhere around Apollo 14/15 where the main purpose of the missions started becoming scientifically exploring the moon.
That's something like 25 crewed flights at various stages of development that had as their purpose to explore/learn about just one or two new aspects of the future moon missions, pushing the envelope a little further.
Granted, many of these things we have fresh practise in thanks to the space station, but also many of them we don't. It seems a little weird to bet it all on a small number of big bang launches.