e.g.,
My two friends who got early screening had a few false positives, and one true positive treated early. One later died of heart attack and one lived long enough to get dementia.
My two friends who didn't get early screening, one died of heart attack and one died of cancer that could have been caught. Both died earlier than two above.
Sadly, at this point, you want to die of cancer, but you want to do it when you're 85. It beats a sudden heart attack and it beats dementia. You just want to prolong the outcome.