The real question is how many UUIDs are generated per second around the world. This RFC suggests using them for automated processes, transactions, etc and generally seems to view them as an inexhaustible resource. If humanity collectively generates 1 trillion per second we can expect to see a 51% chance of collision in 8 months; if it's 100 billion it'd be 10 years, and if it's only 10 billion it'd be 100 years. I would expect even just one single computer with a modest GPU could get in the ballpark of these numbers if it wanted to just spawn UUIDs all day, let alone a huge server farm using them as part of some automated process.
For comparison, before UUIDs most databases were using auto increment integers. That means nearly everyone had id 1, 2 etc in use. Still not a problem.
"The UUID generation algorithm described here supports very high allocation rates of 10 million per second per machine or more, if necessary, so that they could even be used as transaction IDs."
This is the use case they had in mind when building this algorithm, and it would only take about 10k machines worldwide to reach the above levels.
There is a solution that doesn't require extending UUIDs (which has a storage cost everyone pays), which is to use a URI/URN instead of a UUID to provide a namespace. In practice this already occurs, except the namespace (scheme, path) containing the UUID is implicit, as it hasn't been named.
Friends don't let friends use malicious clocks!