Ask HN: How many positions should I apply for at the same company?

In the case of companies that have many open positions (Microsoft, etc.), I'm not sure how many of the positions to apply for. Currently I'm only applying for one at a time.

Background: I'm job searching (Senior SWE) and not getting traction anywhere -- not even getting automated rejection emails when positions are filled. Maybe I'm getting flagged as a bot? Not sure. I'm a generalist (frontend, backend, SRE, lots of languages) which is a blessing and a curse: many of the positions could be a good fit, but I'm not a perfect fit for any particular one.