It depends whether the value of science is human understanding or pure prediction. In some realms (for drug discovery, and other situations where we just need an answer and know what works and what doesn’t), pure prediction is all we really need. But if we could build an uninterpretable machine learning model that beats any hand-built traditional ‘physics’ model, would it really be physics?

Maybe there’ll be an intermediate era for a while where ML models outperform traditional analytical science, but then eventually we’ll still be able to find the (hopefully limited in number) principles from which it can all be derived. I don’t think we’ll ever find that Occam’s razor is no use to us.