Wasp (https://github.com/wasp-lang/wasp) has actually worked out quite well! It just crossed 10k stars on GitHub and is currently the fastest-growing full-stack framework for React & Node.js. It's being used in both startups and enterprises.

Although Wasp has its own DSL/compiler, the secret to its adoption is probably that it works with the existing stack, like React & Node.js. From the developer's perspective, it feels like a framework; the "compiler" part is just what gives it its superpowers.