Drug resistant bacteria found on ISS mutating to become functionally distinct
nasa.gov
nasa.gov
Long periods in zero gravity impair astronauts' immune system. Astronauts experience skin rashes and upper respiratory symptoms from mild to difficult during long-duration spaceflights.
New bacteria in a closed environment with immune-compromised people can be life threatening if they can't get back to the Earth.
Pneumonia in space could kill. Gravity is used to clear lungs. Postural drainage https://www.physio-pedia.com/Postural_Drainage positions help to keep lungs clear. Astronauts drowning in their own fluids one after another would kill long range manned missions for NASA.
https://theconversation.com/as-if-space-wasnt-dangerous-enou...
You can use quarantine to guard against many virus infections, but bacteria that always gets into space with humans is persistent threat. It's annoying when near Earth, but Mars missions must learn how to deal with emergencies.
Submarines and Navy ships have similar dry air.
You see a similar weakening of the immune system in people who obsessively disinfect their homes. Our immune system needs to be exposed to stuff constantly.
This is why I find the idea of humans colonizing the galaxy ridiculous. It won't happen unless we change our bodies substantially. We're just animals. Animals fit to the conditions of earth. (But quite honestly, it'll likely be machine intelligences that inherit the stars instead of us with our biological shortcomings.)
As far as living on other planets goes: there is gravity. What we don't know is how much gravity we need. We could answer this with a space station with spin gravity by trying different rotational velocities and monitoring the health effects.
The Moon has about 1/6 Earth gravity. Is that enough? We don't know. Mars has a little over 1/3.
Long duration space flight probably needs spin gravity too. There are two ways to do it. One is a torus shaped spacecraft. The other is two spacecraft and a tether where once they insert themselves into their cruise transfer orbit they link, extend the tether, and start orbiting each other in a spin configuration. People could go between the ships if necessary by following the tether, though this would probably only be done when strictly necessary due to the risks.
There's a calculator online for spin gravity based on what we currently know about human tolerance for the Coriolis effect:
https://www.artificial-gravity.com/sw/SpinCalc/
It's not too bad. There are various workable sweet spots. Playing around I find one at 20 meter radius and 0.66g (2/3) gravity. It looks like you can't get much smaller than 15 meters diameter without ill effects, but we actually don't know. We need to try this to see what humans can actually adjust to.
The simplest test short of a centrifugal station would be to put two capsules or Starships in orbit and tether them and experiment with different tether lengths and rotational velocities.
Edit: actually there's a third way to do gravity on long duration flights. If you watched/read The Expanse you saw it. Accelerate to the midpoint, flip, decelerate to the destination. Unfortunately that requires insane physicsts' nightmare propulsion systems like the fusion engines in The Expanse that we do not have and won't have for the foreseeable future unless there are some crazy fusion breakthroughs.
The Expanse subreddit has a lot of people doing math on such things.
https://www.reddit.com/r/TheExpanse/comments/128c8rv/update_...
The biggest of these is that IRL those ships would have to have large heatsinks. Even if the drive were phenomenally efficient you're going to have a minimum of hundreds of megawatts of waste heat to radiate into space to avoid melting the ship.
The second one is that the drive itself would be a deadly weapon. Those scenes in The Expanse where they fire up the drive near other ships or near space stations? Nope, not unless you want to fry everyone on board with X-rays. You wouldn't fire up a drive anywhere near anything you didn't want to cook with hard radiation.
This last point is known as Jon's Law in space engineering and sci-fi: any sufficiently powerful space drive is also by definition a weapon of mass destruction.
https://tvtropes.org/pmwiki/pmwiki.php/Main/WeaponizedExhaus...
So this is another area where bringing down cost of pound to orbit is highly impactful. If that becomes cheap, it becomes feasible to build in orbit crafts (orbital stations, ships, etc) sufficiently large to support human-friendly habitats. Should Starship+Superheavy succeed, it will be a significant step forward in this regard since it can put the interior volume of the ISS in orbit in a single launch, and perhaps in a few decades use of resources mined from asteroids could become a consideration.
I guess the answer could be that the sideways motion will drive you crazy due to coriolis forces? See 6 minutes in https://www.youtube.com/watch?v=nxeMoaxUpWk
But they can just substitute windows with monitors that compensate for the view.
Incidentally, the viewscreens on Star Trek etc. always had the ship right side up, so they probably compensated exactly in this way :)
Needless to say, we have no idea yet how that would even be possible :) So, for now, the question is whether we can still do it without such a solution.
Imagine all the suffering caused by failed attempts, people living their whole life with bad lungs so a privileged few can get a little closer to their space fantasy. I wouldn't want to be born into that experiment
Sadly, we're not both at the same time and the results are in one of the Sci-fi books.
Unless I missed it.
I think it might be a (bad journalistic attempt as a) general descriptor for the species/ strain of bacteria studied, but maybe I'm reading it wrong.
Question is: will it mutate into something which is no longer drug resistant? And is there any compelling reason for it to do so?
Space travel involves humans in an inescapable environment, without access to many medical therapies, and with potentially compromises immune systems! [0]
Seems like a strange choice.
Future news: "Drug resistant bacteria impossible to purge from Starship Mars Flyby 1. Sick astronauts turn strange color, sweat strange substance. Want to come home, but have 90% of their journey ahead. Fearing their novel infection, NASA tells them "Don't come back!", sends them erroneous course corrections. Bacteria researchers from 2024 experiment, jubilant at this dramatic evidence of their success, request more funding and astronauts."
[0] https://www.popsci.com/science/space-immune-system-t-cell-ge...
These bacteria were not intentionally brought to the ISS, they hitched a ride in/on the crews and colonized the station. From the paper [1]:
We obtained 211 assembled genomes, annotated as E. bugandensis, from the publicly available National Center for Biotechnology Information’s (NCBI) GenBank sequence database [20]. Among these genomes, 12 were isolated from three different locations aboard the ISS during the first Flight of the MT-1 mission: four from the Air Control (AC) samples, one from the Advanced Resistive Exercise Device (ARED), and seven from the Waste and Hygiene Compartment (WHC). Additionally, one metagenome-assembled genome (MAG) was recovered from the WHC samples.
Makes much better sense.
Well, we can either pretend it didn't happen and ignore it, or do the opposite and study it well so that one day we understand what makes them so efficient at dealing with X rays and existing drugs.
And... the bacteria which are a threat to humans are exactly the ones we are interested in studying, because knowing more about them helps us figure out how to make them be less of a threat to humans.
> Study findings indicate under stress, the ISS isolated strains were mutated and became genetically and functionally distinct compared to their Earth counterparts. The strains were able to viably persist in the ISS over time with a significant abundance. E. bugandensis coexisted with multiple other microorganisms, and in some cases could have helped those organisms survive.
The bacteria changed (how, why, can we see?), they survived in space (plainly the original bacteria also survived long enough to evolve), and possibly adapted/coexisted with other (unnamed) microorganisms.
And then they were brought back to earth to be studied.... That too surely impacts the study of 'bacteria in space'.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10960378/
There's even a video abstract!
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10960378/bin/40...
> The ISS genomes exhibited an average of 4568 genes, a significantly higher count than the average of 4416 genes found in the Earth genomes.
Yes, 4568 is a significantly higher count than 4416. But if I took samples of this bacteria from different countries, would I see a similarly significantly different count? I've no idea.. is this even significant without this sort of comparison?
I watched the video too. This really is just a bunch of stock footage, with the same info as the linked NASA article.
Do others find this info to be compelling of anything? It seems that this could be a PR piece of some sort, for 'space science'. I don't get the significance.
That bacteria basically evolves to consume energy and evolve to different forms of energy. Like at first it is pulling apart minerals in rocks to eventually pulling plastic bonds apart. Eventually it becomes harmless because energy is abundant on Earth and it seems to be intelligent as it evolves very quickly, and it only kills people in the early evolutions (by accident) and doesn't end up killing the scientists in the lab. Or the rest of life on earth.
Been quite a while since I've seen the movie.
like if we can't terraform terra, how tf are we doing that to a barren rock 1 year away with no atmosphere?
Other planets are… kind super-duper terrible. Space itself is even worse.
But let's just call this evolution and pretend that it explains something of the goo-to-you type of evolution most people think about when talking about evolution!
2. That's your own interpretation of the word. The actual definition of extraterrestrial life is life that did not originate on earth.
While I would not consider something that evolved on a space station around Earth as extraterrestrial, this seems a bit restrictive. This would rule out any life evolving from Earth material on Mars brought by a rover as extraterrestrial even million years later. Also, if we discovered life came from an asteroid, we might have to consider ourselves as extraterrestrial with such a definition.
(though I would not know how to define the word)
maybe war of the worlds was a warning about private space exploration more than anything else. imagine being invaded by aliens with good protocols.
Also its gamer tag