Vastly more expensive. Leaves 95% of the fuel unburned & extremely dangerous for thousands of years.
For me, the problem with nuclear is the safety profile: although the mean deaths per TWh is really really low, the observed upper bound on damage that can happen when it does go wrong is sufficient to bankrupt a superpower.
Low mean/high variance is exactly the kind of scenario where I expect people to cut corners because they think it will never affect them.
Then there’s the efficiency that diminishes over time, and a much shorter life span.
Compared to stable output and 40-50 years of power generation. And much lower environment impact overall (especially compared to the power generation over its lifetime)