Hacker News Reader

I've heard from random podcasts (do your own research) you need to make sure you exercise, and perhaps eat high protein, while on drugs like this, otherwise you lose a ton of muscle mass. Could be deadly for seniors, where falls are a leading cause of death.

See https://www.ncoa.org/article/get-the-facts-on-falls-preventi....

This is not to say the drug is bad, simply to encourage education so we dont trade one problem for another.

View on HN

> I've heard from random podcasts (do your own research) you need to make sure you exercise, and perhaps eat high protein, while on drugs like this, otherwise you lose a ton of muscle mass. Could be deadly for seniors, where falls are a leading cause of death.

This isn't true in the sense that it's because of GLP1 RAs in particular -- it's just that GLP1 RAs are effective at rapid weight loss, and that's what happens when you undergo rapid weight loss REGARDLESS of method.

It's a trade-off -- do you want to manage muscle loss and bone density issues (with an easily modifiable dosage/etc) or manage type 2 diabetes or heart disease for the same patient?

Reply on news.ycombinator.com