Other studies already proved those effects with creatine with a normal dose schedule, what they were testing is if a single high dose would have a beneficial effect too, which it did.

A normal schedule is 3-5g per day with an optional loading phase of 10-20g per day during 7 days.

In the study they used a single dose of 0.35g/kg which means 20-40g per dose. How do they not get diarrhea? The loading phase is usually split into several doses to avoid diarrhea and I can personally attest to that being a good idea.