It doesn't need Multi-Account Containers. You can run any browser (or program) as long as it allows specifying different user profiles from the command line. I'll test it with firefox and let you know.
I tested it and it works as expected. Also fixed a few things and released a new version (so please upgrade if you already installed it `pipx upgrade browser-hub`). And here is an example config for Firefox: https://github.com/amirkarimi/browser-hub?tab=readme-ov-file...
Please don't forget that you first should create the profiles in Firefox, since it doesn't create them automatically.