Admittedly, it took a few decades after the Nuremberg trials before the superficial realization that you can't do everything that pleases the researcher's heart took hold.
"The ancient Persian kings and the Egyptian pharaohs are said to have treated criminals as expendable experimental material, much as a modern laboratory researcher might order a supply of rats or rabbits. The practice was apparently still in vogue in eighteenth-century England, since Caroline, Princess of Wales, "begged the lives" of six condemned criminals for experimental smallpox vaccination before submitting her own children to the procedure. (She also procured, for further trial, "half a dozen of the charity children belonging to St. James' parish/')"
Louis Lasagna, Special Subjects in Human Experimentation, p.449, Daedalus Vol. 98, No. 2, Spring, 1969, Ethical Aspects of Experimentation with Human Subjects