But, FWIW, I've been really happy with acmeplus's beta of Batocera Linux on my RG35XX+. My son and I have been taking turns playing through old gems like Pokemon and Aladdin on it, and I'm hoping to finally beat Final Fantasy VII one of these days.
By the PS2/GameCube/Xbox era most games were fine and PAL60 was becoming a thing anyway, but older than that and there’s a good chance the game just runs 17% slower due to the 50/60Hz difference, or has some weird letterboxing due to not accounting for 576 vs 480 lines.
I still remember the first time I saw an imported Japanese PS1 playing Teken 2, and how much smoother it looked on NTSC. I could never look at my PAL copy the same way again, I couldn't unsee the NTSC version. For me personally, those extra 10 frames trump the extra 100 scanlines in PAL etc.
A lot of PAL ports of games ran slower because they weren't re-timed correctly if at all. On the flipside, being the last major region to get games, there was often additional content by the time they got here. Like the infamous "European extreme" difficulty in MGS3.
Although, I'm sure US commercial TV stations frame drop movies to speed them up so they can insert more commercials these days anyway.
I can't say how it's done today, but at the TV station where I worked in the 1990's, we did. But we never dropped frames of content. That would cause all kinds of copyright and contract problems.
We did, however, drop frames of black and superblack. In an average hour, we were able to get back enough frames to insert an extra 15-second commercial at the top of the hour.
If you send a signal outside those bands, it's known as a superblack/superwhite. The "blanking interval" (when the beam is meant to start at the top of the screen again) has a signal blacker than any black that would show up in a broadcast. If that were not the case, a black screen in a show would mess up your TVs tracking.