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My girlfriend has pretty bad post-covid, the thing that helped her most was getting on Citalopram. There's suspicions that many SSRI's have a anti-inflammatory effect on the brain, which might be the mechanism.

She's currently in oxygen therapy, we're positive about the effects but since it's dominating her life (and energy) at the moment it's hard to say what the effect is.

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SSRIs have some nasty side effects though, including sexual dysfunction.

For sure, but so does heavy post-covid. It's a trade-off that's well worth it for her. It improved her memory and brain clarity a fair bit to the point that it's doable to get through the days hoping for a cure (or at least a way to get back to a normal life).

FWIW anxiety also results in exhaustion and brain fog, so I'm not surprised that it's had a positive impact in this way, it's just unfortunate that it's not without it's downsides.

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