Then there’s the x-family, which can go up to bonkers levels, like 4 TiB of RAM (and local NVMe).
As a sibling comment mentioned, though, if you can fit the data into local storage, that’s the way to do it. EBS latency, even with io2.blockexpress, simply cannot compete.
That said, if I did the math correctly based on the 71 GB/31 days footnote, you’re looking at about 2.15 PB to load the entire thing, so, uh, good luck.