Not binaries, but I've had success with Shiv[1] which builds a Python application into a single-file package that can be run on any machine provided it has the Python binary installed (but not much else). We use it to ship products that run as-is on both Linux (including WSL2) and macos.

[1] https://shiv.readthedocs.io/en/latest/

I built a Win10 binary with Nuitka just the other day, and was surprised to find the pyinstaller binary had higher performance at runtime. Pyinstaller also had several other advantages, such as producing smaller binaries, and building faster, and Win7 support.

For reference, I kept notes on the exact commands I used: https://github.com/9001/copyparty/blob/hovudstraum/docs/nuit...

I've had better luck with pyinstaller! Nuitka is buggy when you use multiprocessing

I've tried nuitka before, and a recent question that occurred to me was: does nuitka have an option to output just C files? Something like:

  python -m nuitka example.py --no-compile

Might be interesting to see if the above is possible. We could get things like a completely-statically-compiled Python stdlib within the APE.