Not really. These APIs are useful, but they’re still too primitive to make a dent in library usage. To do that you need things like highly capable “batteries included” (yet easily customizable) widgets and the more generally applicable parts of React (or similar) implemented as browser APIs, so for the majority use case few or no third party libraries or layers are necessary.
The end goal here would be to have a basic reactive UI development toolkit complete with a full spread of ready to use widgets with nothing but a plain text editor and a browser.
That won’t meet everybody’s needs of course, but even those still using third party libs would benefit since things like React could be lightweight “sugar” libraries built on the browser APIs instead of hulking behemoths with a fractal spiral of dependencies.