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There appears to be some correlation between Ehlers-Danlos Syndrome and autism

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7711487/

It makes a certain amount of sense that a collagen / connective tissue disorder is going to have wide-ranging effects, including the nervous system

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Another way to think of this is that 'autism' is a broad series of disorders where individuals do not follow the social-relational cues we expect. There are many ways to violate unspoken social expectations, so there should be many ways to be autistic.

In this setting, it's not unreasonable that any genetic syndrome would be more associated with autism; indeed, it's more interesting to find lesions that have a lower proportion of autistic carriers compared to the general population.

Yeah, I suspect it's quite likely that autism is correlated with/caused by genetic disorders in general, rather than being its own thing that just happens to be comorbid with a suspicious number of other disorders.

There's too many correlations that aren't common enough, I really think we've got the causality backwards. But then again I don't know anything

Wow, I'm hypermobile and my sons have what appears to be mild autism (see my other comment above). Yet more to unpick!

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