What annoyed me the most is actually clicking on ads from Google Search. Sometime I searched a product and I couldn't clicked on the first result because they are advertisements.
I'm typing this response not to smugly boast, but because it's a lead in to the question that your comment raised within me:
Are you using Pihole to block ads at a network level, but not also using a browser extension to block them at the client?
So in my case, I don't know that an ad blocker really even helps me on google, because I'm ignoring those first results anyway.
A lot of Pihole users don't bother with browser extensions. In extension-only use cases, these results would just not show up. With Pihole, you have to copy and paste the URL and just enter directly in the browser. It's not like a huge roadblock.