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> use them as a last option when you have exhausted all other choices.

if one wants to run service with high availability (no downtime if server died), what are other choices then?..

Load balancers in front of a Proxmox cluster + Ceph storage (managed inside Proxmox) + federated/replicated databases (MySQL/MariaDB/Postgres etc)

Which sounds like self managed quite complicated distributed infra..