It would definitely be quicker if you could get someone like that on board right away. It's just not a given that that's possible. Depends on how compelling your idea is, etc.

But if you're already familiar with the trio, that's all you need to get started. Try to go ahead and build your prototype with Express.js, a Node.js web framework.

Server-side/backend:

http://expressjs.com/

http://nodejs.org/

Client-side/browser/frontend frameworks:

http://twitter.github.com/bootstrap/

http://ajkochanowicz.github.com/Kickstrap/

http://html5boilerplate.com/

Tutorials for HTML5 Rich Web Apps:

http://www.html5rocks.com/en/