Saturn Emulation is definitely possible but the amount of complexity in the hardware means that it's much more resource intensive than its 32-bit contemporaries:

https://mednafen.github.io/documentation/ss.html#Section_int...

>Mednafen's Sega Saturn emulation is extremely CPU intensive. The minimum recommended CPU is a quad-core Intel Haswell-microarchitecture CPU with a base frequency of >= 3.3GHz and a turbo frequency of >= 3.7GHz(e.g. Xeon E3-1226 v3), but note that this recommendation does not apply to any unofficial ports or forks, which may have higher CPU requirements.

Those minimum specs are about the same as what's required to emulate a Wii via Dolphin, two generations ahead of the Saturn!

Yes, it's really quite good right now, and very accessible under programs like OpenEmu. I have a Saturn hooked up to a CRT still, but the emu doesn't feel very different these days.