Async/await with one thread is simple and well-understood. That's the Javascript model. Threads let you get all those CPUs working on the problem, and Rust helps you manage the locking. Plus, you can have threads at different priorities, which may be necessary if you're compute-bound.

Multi-threaded async/await gets ugly. If you have serious compute-bound sections, the model tends to break down, because you're effectively blocking a thread that you share with others.

Compute-bound multi-threaded does not work as well in Rust as it should. Problems include:

- Futex congestion collapse. This tends to be a problem with some storage allocators. Many threads are hitting the same locks. In particular, growing a buffer can get very expensive in allocators where the recopying takes place with the entire storage allocator locked. I've mentioned before that Wine's library allocator, in a .DLL that's emulating a Microsoft library, is badly prone to this problem. Performance drops by two orders of magnitude with all the CPU time going into spinlocks. Microsoft's own implementation does not have this problem.

- Starvation of unfair mutexes. Both the standard Mutex and crossbeam-channel channels are unfair. If you have multiple threads locking a resource, doing something, unlocking the resource, and repeating that cycle, one thread will win repeatedly and the others will get locked out.[1] If you need fair mutexes, there's "parking-lot". But you don't get the poisoning safety on thread panic that the standard mutexes give you.

If you're not I/O bound, this gets much more complicated.

[1] https://users.rust-lang.org/t/mutex-starvation/89080