We seem to have reached peak education a few years ago, and I don't see it growing much more in the next decade. Their public k12 schools are still amazing, but that's more so a testament to the outer suburbs than the core urban area. Public transportation was a huge draw, and it's in dire straits. The 'next tech hub' thing never took off, with Austin, LIC, NJ & Atlanta growing faster than Boston. Biotech is doing great, but as it moves from academia to industry....I'm seeing a slow siphoning of biotech talent into the bay area.
The biggest issue is how well NYC is doing. Boston was always a great way to experience NYC-lite. But the mass gentrification of LIC, Brooklyn and Jersey City has now made it possible to have NYC-lite within NYC itself. So it makes Boston less appealing.
As far as cities go, Boston is still doing amazing. But I am going to change my optimism around it from 'best positioned to see massive growth' to 'good city that does 1 or 2 things well'.
Thankfully for Boston their problems seem solvable. Give incentives to MIT/Harvard grads to set up startups locally. Make it easier to build housing and fix public transport....the city will be back to #1 on my highest growth potential list.
P.S: I say this in jest, but make DeSantis ship a few more migrants up to new england. The Mexican food scene is trash and needs help.