Figured people can Google, all I bring is awareness this is widely overblown, having taken myself, for therapeutic purposes, upwards of 100k IU per day for months without doctor supervision (but doing it correctly, with a very low calcium diet). People take vit D megadoses for autoimmunity, with significant success, but I'm not discussing this here.
As with anything fat-soluble it's wise to take it as part of a meal that includes plenty of fat.
The problem with most studies is, surely in part because of this unfounded fear, they are underdosed. I don't have anything on hand, but I know there are clinics supervising megadose vitamin D protocols all over the world, but mostly in Germany and Latin America, that I'm aware of.
I have been diagnosed with some autoimmunity issues and would love to try this. How did you identify that vitamin d might help with yours?
When I had my first major flare-up, I tested at 7ng/dl (near bottom half of the severe deficiency range). That's what lead me to pay attention to this subject.
You mean for compensating for the low vit D levels due to constant inflammation seen in autoimmunity? or to decrease autoimmunity? I have autoimmune diseases and my vit D goes down to about 7 ng/mL without supplementation, so I'm curious.
Per your question, the latter, the theory is autoimmunity is exacerbated in a certain genetic makeup, and to compensate for it by megadosing.