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Related to strange things running in spreadsheets, if you want to see how a 16-bit CPU works, Inkbox has created one in a spreadsheet:

A twenty-four instruction assembly language is also provided.

It's since changed, but for a while the band [Portugal. The Man]'s website was just a Google Sheet!

Reminds me of way back when I wrote a simple 8086 assembler in Lotus 123. It even worked for simple uses.

Lotus 123 would have been more popular with programmers if it were named Lotus 012.