Or, uhm, how to play it at all. Maybe I'm just really bad at this game, but I always end up dying to lack of oxygen within the first hour.
Every now and then when they patch the game they also include an expedition where you do a little storyline with a buffed character. Wish they were permanant but if you keep an eye out they are a good way to kill a weekend.
By default I just run everywhere, in basically every game. I think a lot of gamers do.