Tons of people scared of mental and other forms of decline here. Hey, I got news! It's 2024. We understand a fair deal more of how our biochemistry works. We have more computing power than ever, and it's going to be increasing thanks to the crazy amounts of computing power our latest AIs need. That means that we can understand even more of how our biochemistry works by doing exactly what each drug company is doing: running computer simulations. If your eventual decline scares you, it's unlikely that you can change your outcomes. But not impossible. It's still perfectly rational to find your peace in resignation, but it's not the only option anymore.