Probably a bit yeah. But there is an argument that it is hard to store a lot of chemical energy without abundant oxygen in the environment. Oxygen stores a ton of energy, and it's quite difficult to achieve comparable energy density without it. This is the basic reason why gasoline has so much more energy than batteries, and people are developing batteries that use oxygen from the air to increase energy density. I remember reading in a Wikipedia article that Earth's atmosphere before it became oxygenated would likely not have been able to support multicellular life with energy-intensive things like muscles and complex brains.

But without knowing if Europa has any life at all this is probably putting the cart before the horse.

It’s not that it needs to be, it’s just that—based on our knowledge of the chemical elements—life based on some combination of oxygen, carbon, hydrogen, and nitrogen is by far the most likely.

Other forms are certainly possible, it’s just that they are highly highly unlikely to form and remain stable, and develop into complex intelligent life.

So all of that informs where you should focus your efforts on research and searching.

It doesn't. There's plenty of anaerobic life on earth.

The only intelligent life we know of is, and has energy demands within the bounds requiring oxygen powered metabolism.