We emulate neurons mathematically but it is possible to build efficient analog circuits that emulate them physically.
I doubt any biological system can ever learn all the information gpt4 has learned. The gpt4 learning may not have been power efficient but neither were the first airplanes compared to birds yet today biological flight is rather limited compared to flight that uses technology.
Ever listen to Geoffrey Hinton speak about back propagation vs what biological systems use? Do you think he is wrong about this?