Is this related to ritonavir's multiple crystal structures (https://en.wikipedia.org/wiki/Ritonavir#Polymorphism_and_tem...)?
> Perfect crystals. Also, the proof-of-concept drug was ritonavir, and it's nearly impossible to consistently grow large crystals of it on Earth. All of the labs that work with ritonavir are contaminated by a more stable form ("polymorph") that rapidly converts any ritonavir crystals into a less-useful form.
In short: yes, you're correct, but I am just parroting somebody else; personally, I posses no actual knowledge of chemistry involved.
(This sounds like such wizardry.)