It’s a language which feels like it has a lot of magical incantations you need to remember - the default namespace is much more crowded. Functions like sapply vs mapply are tricky to reason about from the documentation alone. The values NA vs Null vs integer(0) are all used as standins for real thrown errors and knowing which one to check for after calling a function can be tough.
But after using it for a few hundred hours to do data processing and statistical regression it’s hard to imagine python or Julia being faster to use. But in all honesty for the pharmaceutical industry it’s mostly momentum that keeps R on top same reason they use a lot of FORTRAN90.