* Basically everything FromSoft has put out (With Dark Souls 1 and Elden Ring probably being the most important - Dark Souls effectively kicked off an entire genre because of it's popularity (technically Demon's Souls came first, but Dark Souls was the first one to blow up).)
* Breath of the Wild
* Escape from Tarkov also kicked off a new genre in the extraction shooter, although noone else has quite nailed it yet imo.
* The Witcher 3 (heavily influentual towards the design of Breath of the Wild, and a number of other open world rpgs recently)
* As someone else pointed out, Baldurs Gate 3
* Skyrim
* Minecraft
* Dwarf Fortress (not exactly recent, but the Steam release propelled it into being much more well known)
* Path of Exile arguably revolutionized the diablo-style ARPG genre - any ARPG that comes out now is influenced by it - see Last Epoch for probably the biggest example.
Whether a game is "culturally relevant" or not really just hinges off of whether a significantly large portion of the population plays and talks about it for long enough though.
These days we get so many more quality game releases than we ever did in the 90s/2000s so it's much harder for a single game to grab everybody's attention in the same way that the stuff you mentioned did.