Well Temperaments (Part 5)
johncarlosbaez.wordpress.com
johncarlosbaez.wordpress.com
For instance, Logic Pro
https://support.apple.com/guide/logicpro/tuning-project-sett...
Many DAWs stay out of tunings and leave that for the individual virtual instruments. There's a standard for that named Scala (yes, also a language).
MPE is a pretty good first step, but you also need good support in composition software and DAWs.
I know some people who compose in 41-TET using Musescore. I think it requires some plugins.
One of the nice things about modular synthesis is that it uses control voltage for pitch, which is continuously variable. There's no built-in tuning system assumptions at all, even though individual modules may bring some 12-TET baggage with them. On the other hand, getting analog oscillators to track the volt-per-octave standard accurately enough that these subtle distinctions in pitch don't get lost in unintelligibility is easier said than done. 3340-based VCOs seem to do a decent job but they have to be calibrated carefully.
However, temperaments allow some composition tricks that are impossible in JI. Tempered systems basically merge annoyingly small intervals that appear in JI, so you can create progressions that would be otherwise impossible.
Either way I fully agree that more musicians should be exploring JI and alternative temperaments, and I'd like to believe that it's the future. A lot of people who go down this path fall to the nerd-sniping you mention, and they end up only exploring technique while losing track of musicality. It's hard to find balance.