The "work from home" is definitely a "your mileage may vary"
The operative part there is that it is the poster's decision. I think most of us who have the resources to begin a startup or afford renting a coworking space also have the ability to be somewhat mobile within our local geographic area. Americans in particular are known for moving quite often.
To conclude, I think that considering a walkable or bikeable commute or the availability of public transit is great advice for anyone who is planning on moving within the next five years — which is nearly 75% of the US population.
As for schlepping through traffic, that wouldn't bother me so much if I wasn't trying to get to the office on a strict time schedule. Flexible office hours with work-from-home days sounds comparatively paradisal.