Wirebonding is here to stay
semiengineering.com
semiengineering.com
Whoever finds a way to sidestep this problem in a straightforward manner, would be a rich person for sure.
In other words: "packaged" IC's are here to stay, things like flip-chip apply only to specific segments, and thus wirebonding is here to stay.
I know that some dies are super tiny and this could make it difficult at the pcb bonding level, but surely we can shrink down our usage of plastic and the alloys that go into the IC packages. Theres a lot of unused space inside an IC package, with most of it being empty or pin arms. That would allow for smaller and more dense boards.
Mobile phones today largely use chip scale packages that do not use any sort of wire bonding, for instance.