More fundamentally, quantum systems are inherently random. You literally can't know the exact future of hundreds of atoms in perpetuity--that's not how quantum physics works.
But you can get an idea of minimum energy states, the energy barriers holding those states in place, and therefore what the stable outcomes might be.
EDIT: I thought I'd double check that since it's been a while since I studied physics formally; apparently it is possible to model light nuclei[1] (up to four nucleons) from the ground up now!
[1] https://en.m.wikipedia.org/wiki/Ab_initio_methods_(nuclear_p...
[1]
It's like polynomials: there's a quadratic formula, and a cubic and even quartic formula for exact solutions (although the quartic is ridiculous and no one would ever use it). Higher order polynomials have NO exact, closed-form solutions using standard arithmetic operations. But we can still solve any polynomial no matter the degree using numerical methods. To say that we don't even know how how degree 5 polynomials work would be flat out wrong.