If you look for 2FA with otp, email, sms and also passkeys foe self-hosting, then give zitadel a spin. All features are included in the open source version. Should also work nicely with docker compose + nginx. In case you have issues, join the chat.
https://github.com/zitadel/zitadel
TOTP 2FA is free. SMS and email MFA are part of the paid plans.