But, there was definitely pains with this kind of desktop when I tried it last time. Regular old software I want to install via dnf is painful to install - you have to layer it on top of the base image, and then that makes it "nonstandard" basically from then on. I know they push you toward flatpaks, but the vast majority of apps I use don't have it (or I don't prefer using the Flatpak version).
Can anyone give a more recent perspective? It's been about two years - I probably used Fedora Atomic 35/36.