Appendicitis was around in ancient times, too, so I am not sure I understand the reference only to industrialized nations in that respect.
I saw it as a reference to fiber poor diets....
Unless you're experiencing gnosis while noshing, in which case carry on. I've had prunes that good before.
If you're experiencing gnashing while noshing, then I suggest taking a break and changing to a different activity.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9758930/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9945388/
Bangladesh and Bhutan have the highest age-standardized prevalence rates, for example. One of the lower SDI cohorts seems to lead now.