If I may add my two cents, I think you should concentrate on making it possible to go beyond lumped element models (which can already be simulated using SPICE, etc) and simple abstraction (solved by VHDL & co) and focus on being able to offer advanced subsystems to less experienced PCB EDA users. Basically, to go for the Altium path, but without Altium. For example, it would be a killer feature if it were possible to import an FTDI USB chip module and a switching power supply module, and obtain a PCB that has a guarantees (up to a degree) that the two will not interfere with each other. Or say, have it automatically optimize a design to guarantee a certain SWR [3].
[1]: https://www.analog.com/media/en/training-seminars/tutorials/...
[2]: https://f4pga.org/