JavaScript is one of the most popular programming language. But a JavaScript dev who needs to make a desktop GUI will usually need to use Electron to bring up a browser for the GUI. This means actually two JavaScript engine (Node and Chromium)
The reason it has to do with Deno is that you need a JavaScript/TypeScript runtime. But you may not need a browser. So you can develop your application in JavaScript using a framework that doesn't use the DOM but show a native window instead.
This is more lightweight and more secure (no risks of HTML injection and the browser is a big attack vector)