Imagine trying to go to a place right now where suddenly you weighed 3x as much. In all probability, you would die without some sort of special assistance - probably of some sort of cardiovascular failure. If you're a 180lb male, it's the equivalent of strapping a 360lb weight suit on yourself, with the relevant difference that lying down wouldn't offer even the slightest of respite from the forces being imposed on your body. It also has interesting implications for sports, which are just going to be awesome in low g. An Earther would have a massive and tremendously unfair advantage against a Martian.
There's going to be some dramatic (and rapid) social, physical, and even evolutionary drift.
Which is necessary to go any meaningful distance in space anyway