What do you mean by "tried-and-true alienation"?
Alienation means the breakdown of social ties and the fragmentation of identity. Durkheim published theories on this stuff well over 100 years ago. He also studied suicide.
I agree that we're probably seeing a continuation of trends that began long ago and that are tied in with capitalism, urbanization, and the decline of religion.
I mean this not to imply a structural sense of our society, only the shock that his prediction is insanely accurate given the time and technology separating us.