Unless you want to live in an area where entertainment and restaurants and specialized healthcare and all the other good things are plentiful.
However, as a suburbanite, I have no problem “commuting” to entertainment in the city once every weekend, when previously I had to commute 5 times a week for work. And when I go to the city, it’s a day full of fun/activities because I know I’m not coming back for a week. You can get the best of both worlds that way.
St Louis, Eindhoven and Bordeaux do not have hospitals, good restaurants and entertainment.