Get laser safety goggles that are appropriate for the wavelength of your laser, and get them from a reputable source. Always wear them whenever the machine is powered.
Make sure to have a way to easily and quickly de-energize the laser for when stuff catches on fire, be it an e-stop button or using an outlet with a switch.
And don't ever cut PVC. It'll generate chlorine gas, which will either injure/kill you or corrode your machine.