When I was trying to determine whether an air-source heat-pump could work to replace my old (like 1950s old) gas boiler, what I did was reduce the flow temperatures leaving that old boiler to see what flow temperatures would be required to satisfy the heat loss at various outside temperatures. (This is basically discovering the required outdoor reset curve on a mod-con boiler.)
I found the minimum temperature to maintain 71°F at various outside air temperatures and then looked to see whether the ASHP could provide that flow temp (sometimes called "leaving water temp"). (This is also what the article's author did.)
In a case like that, I'm inherently proving that the pipes are sufficiently sized as well. Now, the downside is that it requires time and effort on the homeowner's part, requires a working old boiler, requires a winter season of variable temps, so it's not a practical way for a contractor to bid the job, but for HN readers, you can do it that way. (Note also that if your old boiler is not a condensing boiler, you will be damaging it by causing it to condense acidic water from the exhaust. I was OK with that, because I knew it was going to be replaced the following year.)
If I found that the house struggled to maintain temp, that method doesn't tell me whether increasing the pipe size would help (though having a larger than desired delta-T coupled with a low flow rate is a strong hint).
For a contractor bidding/design situation, there is a universal hydronics formula which is BTU/hr = 500 * delta-T (in °F) * gallons/minute. Pick the delta-T (often 20°F) and the heat load, and solve for gallons/minute. Look up pipe sizing tables for maximum velocity, then using the pipe size and total developed length, figure out the pump you'll need. Then check the emitter sizing to ensure that it can emit the heat required (to "cause" the delta T) at the lower flow temperatures characteristic of an efficient heat pump system.
Ultimately, I proved to myself that a heat pump could work down to an outside air temp of about 18°F [which is slightly above our 99th percentile design temp] with flow temps of 135°F, so an air source heat pump could work with slightly reduced comfort on about 2% of days or could work all the time with supplementation with a 9kW [30K BTU/hr] electric boiler.
What killed the project is no heat pump installer was interested in doing the work (as reflected by outright declining to bid, while bidding a 4-hour gas boiler swap, or by bidding so high that they might as well not have bid, while also cheerfully bidding a 4-hour gas boiler swap). So my house still burns gas for heat, which matches the author's experience:
> this speaks to the third lesson in my story. The boiler market is focused on cheap and quick installation.