I can not talk about your family members as you would have the best context. Only out of curiosity, have you already explored techniques from books like Crucial Conversations or consulted a therapist before cutting connections?

As far as the job is concerned quitting the one you dislike is only 10% of the work, finding the one you like is the 90% of it. I am sure that once you find the one you like you will be far more fulfilled.