That industrialization of beer was a major step backwards; flavourless but cheap lager almost eliminated good traditional beer.
That said, anecdotally, I did see a drop in quality of Pilsner Urquell when they moved from their traditional brewery (which had quite the ecosystem in the ceiling) to the newer one. Lots of folks like to say that the crazy stuff going on over the vats affects the flavor.
The best beer I ever had was draught Pilsner Urquell, sat outside the brewery in Plzeň circa 2000.
Whatever they were doing inside... oh man, Perfection. I'll never forget.