Varying subpixel layouts are one of the major reasons I struggle to take the obsessions of "pixel perfect" designers seriously [1]. It is the kind of notion you can only advocate if you're ignorant of the reality of what is going on. Display aging and resulting color inaccuracies make this even more fun.
[1] Not helped by having worked on products where the designers quoted 25 years (not a typo) as the time required to support all the supposedly necessary profiles, and the resulting build size would have been too big and so we lost a multi million dollar opportunity. Of course anyone opposing this was simply an enemy of quality.
Edit to add: for those unfamiliar https://en.wikipedia.org/wiki/ClearType was a very sneaky way to take advantage of the fact that the subpixel layout dramatically alters the outlines the viewer sees.